Nanomaterials for clinical applications [electronic resource] : case studies in nanomedicines / edited by Natassa Pippa and Costas Demetzos.
- 其他作者:
- 其他題名:
- Micro & nano technologies.
- 出版: Amsterdam : Elsevier 2020.
- 叢書名: Micro and nano technologies
- 主題: Nanoparticles. , Nanoparticles. , Electronic books.
- ISBN: 9780128168769 (electronic bk.) 、 0128168765 (electronic bk.) 、 9780128167052 、 012816705X
- URL:
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- 一般註:Includes index. Front Cover -- Nanomaterials for Clinical Applications -- Copyright Page -- Contents -- List of contributors -- 1. Solid lipid nanoparticles in dermaceuticals -- 1.1 General introduction -- 1.2 Why solid lipid nanoparticles? -- 1.2.1 Formulation aspects -- 1.2.2 Physiological aspects -- 1.3 Evolution of lipidic nanoparticles from solid lipid nanoparticles to nanostructured lipid carriers -- 1.4 Cosmetic and topical applications of solid lipid nanoparticles -- 1.5 Skin penetration with solid lipid nanoparticles -- 1.6 Mechanism of drug penetration with solid lipid nanoparticles 1.7 Incorporation into semisolid vehicle -- 1.8 Case studies of successful topical delivery with lipidic nanoparticles -- 1.8.1 Delivery of antimicrobials -- 1.9 Delivery of agents for other skin diseases -- 1.9.1 Solid lipid nanoparticles for cosmetic applications -- 1.10 Conclusions -- References -- 2. Cyclodextrin-based drug delivery systems -- 2.1 Cyclodextrins-structure, physiochemical properties, and toxicological profile -- 2.2 Cyclodextrin inclusion complexes-formation, stability, and application in drug delivery -- 2.3 Cyclodextrin-based products in clinical practice 2.3.3.1 Cyclodextrins in control of obesity and hyperlipidemia -- References -- 3. Lipid vesicles for (trans)dermal administration -- 3.1 (Trans)dermal drug-delivery systems -- 3.1.1 Human skin barrier to xenobiotics -- 3.2 Lipid vesicles for breaching the skin barrier -- 3.2.1 Conventional liposomes -- 3.2.2 Transfersomes -- 3.2.3 Ethanol-based lipid vesicles -- 3.2.3.1 Ethosomes -- 3.2.3.2 Transethosomes -- 3.2.3.3 Other lipid vesicles -- 3.3 Liposomal formulation in clinics -- 3.3.1 Conventional liposomes -- 3.3.2 Transfersomes -- 3.3.3 Ethosomes -- 3.4 Final remarks -- References 4. Stimuli-responsive nanocarriers for drug delivery -- 4.1 Introduction -- 4.2 Types of stimuli -- 4.2.1 pH-responsive nanosystems -- 4.2.2 Thermoresponsive nanosystems -- 4.3 Development of chimeric stimuli-responsive liposomes with incorporated stimuli-responsive polymers -- 4.3.1 pH-responsive liposomes -- 4.3.2 Thermoresponsive liposomes -- 4.4 Thermotropic behavior of stimuli-responsive liposomes -- 4.4.1 Thermal analysis on pH-responsive liposomes -- 4.4.2 Thermal analysis of thermoresponsive liposomes -- 4.5 Physicochemical properties of stimuli-responsive liposomes 110年度臺灣學術電子書暨資料庫聯盟採購
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- 系統號: 000291919 | 機讀編目格式
館藏資訊
Nanomaterials in Clinical Medicine: Case Studies in Nanomedicines focuses on the nanomaterials that can be formulated as drug delivery vehicles, such as liposomes, micelles, nanoemulsions and nanogels. Their physicochemical, morphological, thermo-dynamical and nanotoxicological properties are analyzed with respect to the design and development of drug delivery nanosystems for the encapsulation of an active pharmaceutical ingredient and its controlled release. Each chapter covers basic properties, the nanosystem (e.g., liposomes), the added value in drug delivery and targeting, and future perspectives. Case studies and examples of how nanomaterials are being used in clinical medicine, including marketed liposomal medicines and medical utility and regimens are also included. Particular attention is given to new nanocarriers, such as elastic liposomes, lipid polymeric hybrid nanoparticles, organogel, nanofibers carbon nanomaterials, quantum dots and inorganic nanoparticles. This book is an important information source for those wanting to increase their understanding of what major nanomaterials are being used to create more effective drug delivery systems. Summarizes the major nanomaterials used in clinical medicine, explaining how their properties make them suitable for this purpose Explains how nanomaterials are used to create increasingly efficient drug delivery vehicles Includes real-life examples, demonstrating how nanomaterials are being used in medical practice